Glucosamine and Chondroitin are common ingredients in supplements for joint pain, specially people with osteoarthritis. Osteoarthritis occurs as cartilage breaks down and it leads pain. Millions of American people have osteoarthritis.

According to Web MD, scientists have been researching benefits of glucosamine alone and together with another supplement called chondroitin for many years, but research results have been conflicting.

Some studies show the supplement reduces knee pain in people with moderate-to-severe osteoarthritis. However, it doesn’t seem to work as well in people who have mild knee pain, have had the condition for long time. Also, Glucosamine was not working for overweight patients with osteoarthritis.